Even for year 2008 GVS group has agreed to adopt a new Cystic Fibrosis Foundation research project with a donation.
Current research is coducted by the Human Molecular Genetics - International Centre for Genetic Engineering and Biotechnology (ICGEB),Trieste, Italy.
It mainly focuses on diagnostic and therapeutic implications of non-canonical splicing defects in disease-associated genes, like CFTR, ATM and BRCA1. Genomic variants that unexpectedly cause aberrant splicing frequently represent a flag put over unknown regulatory splicing sequences. Thus, the study of aberrant splicing in human diseases provides an approach to unravel the basic mechanism of pre mRNA splicing and to design strategies aimed to the treatment of splicing defects.
With this initiative GVS wants to share the effort carried out by Cystic Fibrosis Foundation and its many researchers, and to tangibly contribute to the life expectancy of the numerous Cystic Fibrosis patients.
